Introduction: Diabetes is a chronic hemoglobin disease, one of its characteristics is hyperglycemia, which can cause fatal complications. One of the criteria for diabetic diagnosis and control is fasting blood glucose. On the other hand, the use of traditional herbs for controlling blood glucose has become more common in recent years due to its small side effects. Therefore, the purpose of this study was to investigate the effect of barley juice on glycosylated hemoglobin in patients with type 2 diabetes.

Materials and Method: This was a clinical trial study. 70 subjects who participated in this study were entered into the study by objective sampling method and randomly divided into two groups of users of pill and consumed barberry juice. Glycosylated hemoglobin was initially measured. Then the groups were treated with pill for 6 weeks and barberry juice was added. Data were analyzed by independent t-test and paired t-test in SPSS software version 22.

Results: Based on the results, there was no significant difference between the mean glycosylated hemoglobin group and the barberry juice before the intervention (P = 0.44). Also, after the intervention, there was no significant difference between the mean glycosylated hemoglobin (P = 0.71).

Conclusion: Considering the significant decrease in glycosylated hemoglobin level in each group before and after intervention, plant protection can be recommended and barberry juice is recommended to diabetic patients, thus reducing the complications of this disease