Introduction: Now days, diabetes is prevalent and it can cause severe psychotic effects and depression. Thus, it is necessary to consider effective factors to fight diabetic patients mental disorders. It seems that the role of religion is significant and by augmenting religious attitudes, diabetic patients' depression^’s intensity can be decreased. The purpose of the present study was to examine the relationship between diabetic patients religious beliefs and depression in diabetes clinic of Ali Asghar hospital of Zahedan.

Methodology: This is a descriptive analytical and cross-sectional study. Out of 350 diabetic patients, 70 were selected by easy sampling method. Data gathering tool were Bach's religious beliefs and depression standard questionnaires.   )chi-square) statistical test and Pearson correlation index have been used for analyzing the data.

Results: Obtained results of the study showed that there is not any relationship between age, sex, education, illness duration and family members background of depression with depression.

Conclusion: Results of the study showed that the stronger religious beliefs decrease depression intensity. So it is necessary to strengthen patients religious attitudes by proper plans to decrease depression and some strategies are presented in the study for these plans.