Materials and Methods: In this study, 32 women with type II diabetes were randomly assigned to four groups of yoga training, zinc sulfate supplementation, combination, and control. The yoga-training program included two 70-minute sessions per week during eight weeks. The supplement group consumed 220 mg of zinc sulfate once a day. The combined group both practiced yoga and consumed zinc sulfate supplementation for eight weeks. Blood samples were drawn to measure the levels of serum glucose, insulin, IL-1β, and CRP at two stages of pre- and post-intervention. One-way analysis of variance was used for inter-group comparisons in SPSS software.

Results: The results showed that after eight weeks, there was a significant difference in the mean levels of glucose (P=0.000), IL-1β (P=0.001), and CRP (P=0.000) between the experimental and control groups. However, insulin (P=0.23) and insulin resistance (0.29) did not show any significant difference between the groups.

Conclusion: According to our results, yoga training, consumption of zinc supplement, and their combination could lower the levels of IL-1β, CRP, and glucose. Supplement consumption elevated insulin level and diminished insulin resistance. Thus, zinc supplementation could be considered for the treatment of type II diabetes patients.