Journal of
Diabetes Nursing
Volume 13, Issue 3 (9-2025)
J Diabetes Nurs 2025, 13(3): 73-80 |
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Research code: 130448610612822526015162621601
Ethics code: 130448610612822526015162621601
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Miri A, Vazifedoost M, Didar Z, Hajirostamloo B. Detection of Metformin and Bupropion in Herbal Infusions Marketed for Weight Loss and Type II Diabetes: A Cross-Sectional Study. J Diabetes Nurs 2025; 13 (3) :73-80
URL: http://jdn.zbmu.ac.ir/article-1-680-en.html
URL: http://jdn.zbmu.ac.ir/article-1-680-en.html
Department of Food Science and Technology, Ne.C., Islamic Azad University, Neyshabur, Iran , amirmohsen@iau.ac.ir
Abstract: (738 Views)
Introduction: Over the past decades, the prevalence of type II diabetes has increased markedly, largely driven by the growing rate of obesity. Obesity contributes to insulin resistance, β-cell dysfunction, and ultimately the development of type II diabetes. In recent years, herbal products such as teas and herbal infusions have attracted considerable attention for weight loss and diabetes management. These products contain natural bioactive compounds that may contribute to weight reduction, improvement of insulin sensitivity, and glycemic control. The aim of this study was to investigate the possible presence of unauthorized pharmaceutical agents in herbal infusions marketed for weight loss and type II diabetes. Materials and Methods: Five commercial brands of herbal infusions claimed to be effective for weight loss and type II diabetes were selected. A total of 20 samples were randomly collected from pharmacies in Mashhad, Iran, during the summer of 2024. All samples were analyzed for the presence of undeclared pharmaceutical ingredients using thin-layer chromatography (TLC), with metformin and bupropion used as reference standards. Results: Based on TLC analysis, none of the analyzed samples contained metformin or bupropion. Conclusion: Industrial production of herbal products, when accompanied by strict compliance with health regulations and manufacturing licenses, provides important advantages in terms of safety, efficacy, and consumer confidence. Such regulatory oversight ensures consistent product quality and minimizes the risks of contamination and adulteration, while enhancing regulatory accountability.
Type of Study: Research |
Subject:
Special
Received: 2025/08/8 | Accepted: 2025/09/1 | Published: 2026/02/2
Received: 2025/08/8 | Accepted: 2025/09/1 | Published: 2026/02/2
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