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:: Volume 8, Issue 3 (8-2020) ::
J Diabetes Nurs 2020, 8(3): 1160-1174 Back to browse issues page
Effect of High-Intensity Interval Training and Thyme honey on liver enzymes of type II diabetic rats
Marjan Abdi Ardekani, Abdolali Banaeifar * , Sajad Arshadi, Hossein Abed Natanzi
South Tehran Branch, Islamic Azad University, Tehran, Iran , banaeifar_a@iau.ac.ir
Abstract:   (638 Views)
Introduction: Diabetes type II causes structural and functional changes in the liver resulting in high concentrations of aminotransferases. The purpose of this study was to examine the effects of high-intensity interval training (HIIT) and Thyme honey on the liver enzymes of diabetic type II rats.
Materials and Methods: A total of 36 male Wistar rats were treated with a high-fat diet for 20 weeks and then injected with a 25 mg/kg dose of streptozotocin to induce diabetes type II. These rats with fatty liver were then divided into four groups of control, HIIT, Thyme honey, and HIIT with Thyme honey. Eight weeks, with five sessions every week, of HIIT were designed for the training groups. A Thyme honey daily dosage of 3 g/kg was given to the nutritional interventional groups using oral gavage. Finally, the rats were subjected to anesthesia at the end of the 8th weeks, and the blood samples were taken from the heart. After the measurement of the levels of serum liver enzymes, the obtained findings were analyzed using the two-way analysis of variance and Bonferroni post hoc test. A p-value of less than 0.05 was considered statistically significant.
Results: The obtained results of the current study showed that aspartate aminotransferase and alanine aminotransferase in the HIIT with Thyme honey group significantly decreased, compared to those reported for the control, HIIT, and Thyme honey groups. In addition, alkaline phosphatase in the HIIT with Thyme honey group significantly reduced, compared to that of the control group; however, this decrease in comparison to those reported for the HIIT and Thyme honey groups was not significant (P˂0.05).
Conclusion: It seems that HIIT and consumption of Thyme honey, both alone and interactively with greater effectiveness, can help reduce the liver enzymes in diabetic rats.
Keywords: Diabetes Type II, Liver Enzymes,  High Intensity Interval Training , Thyme Honey
Full-Text [PDF 603 kb]   (433 Downloads)    
Type of Study: Research | Subject: Interventions for diabetes
Received: 2020/08/18 | Accepted: 2020/10/7 | Published: 2020/11/7
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Abdi Ardekani M, Banaeifar A, Arshadi S, Abed Natanzi H. Effect of High-Intensity Interval Training and Thyme honey on liver enzymes of type II diabetic rats. J Diabetes Nurs. 2020; 8 (3) :1160-1174
URL: http://jdn.zbmu.ac.ir/article-1-419-en.html

Volume 8, Issue 3 (8-2020) Back to browse issues page
فصلنامه پرستاری دیابت Journal of Diabetes Nursing
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