Introduction : Diabetes and depression are closely related to each other. The incidence of depressive symptoms in patients with diabetes is twice more than non-diabetic patients. Depression is considered as an independent predictor of the onset of diabetes. However, approximately in two thirds of diabetic patients depression is not diagnosed and remains untreated, which as a result, leads to worsening of diabetic complications. In order to improve both disorders, application of a proper diet as a basic strategy for depression management seems to be necessary.

  Methodology : In order to retrieve the English and non-English published articles on this issue, PubMed, ISI Web Science, SCOPUS, Science Direct and EMBASE databases were searched during January 2000-May 2013.

  Results : Few studies have been conducted on diabetic patients. Considering diabetic complications such as renal and coronary heart diseases, determining the appropriate range and type of various macronutrients is of utmost importance for diabetic patients suffering from depression. In the present study, the available data regarding the treatment of depression in diabetic patients have been investigated.

  Conclusion : Isolating the impact of a single nutrient on the final results is particularly difficult. Given the pathophysiological similarity of depression and metabolic syndrome, same dietary recommendations are applicable for both.