Introduction: Diabetes is one of the major stressors in life and lack of control led to inappropriate social behaviors such as aggression. Having mental health and reduce stress in healthier patients can communicate person in the community  and thus receive better health care help, Therefore, this study aimed to investigate the relationship between perceived stress and aggression in patients with diabetes type II..

Methodology: This study is a descriptive correlational study. 150 patients were randomly chosen, Perceived Stress Scale (PSQ) and and Aggression Questionnaire of Buss & perry were applied to obtain data. To analyze the data, in addition to descriptive statistics, inferential statistical analyses including Pearson correlation coefficient and t-test were performed using SPSS.

Results: The results showed a significant  positive correlation between perceived stress and aggression of diabetic patients (P = 0.001, r = 0.66). That will enhance the perceived stress score, score increases aggression.

Conclusion: short-term and long-term programs in order to identify stressors and strengthen coping skills, can patients for the prevention and control aggression and ultimately receive better health care, be considered as a target.